Based on available data, here are the top 10 most profitable YouTube categories:

1. Making Money Online: This niche has consistently been among the top earners on YouTube, as people are always looking for new ways to make money. Creators in this niche can provide tutorials, tips, and strategies for earning money online, through affiliate marketing, dropshipping, freelancing, or other methods.

2. Personal Finance and Investments: Personal finance is another evergreen niche with a large audience. Creators can teach viewers how to manage their money, invest wisely, and plan for their future. Videos on budgeting, debt management, and retirement planning are particularly popular.

3. Technology and Gadgets: Tech enthusiasts are always eager for the latest news and reviews on gadgets, smartphones, computers, and other tech products. Creators can provide in-depth reviews, comparisons, and tutorials on using these products.

4. Gaming: Gaming is a massive industry, and YouTube is a major platform for gamers to share their gameplay, tips, and strategies. Creators can focus on specific games, genres, or platforms, and they can also monetize their channels through sponsorships, merchandise sales, and fan donations.

5. Lifestyle and Fashion: Lifestyle and fashion are broad categories that encompass a wide range of topics, from cooking and travel to beauty and DIY projects. Creators can share their personal style, provide tips and tutorials, or document their daily lives.

6. Education and Learning: Educational content is always in demand, and YouTube is a great platform for sharing knowledge and teaching new skills. Creators can create videos on a wide range of subjects, from math and science to history and language learning.

7. Comedy and Entertainment: Comedy and entertainment are essential for relaxation and enjoyment, and YouTube is a popular source for both. Creators can share skits, pranks, challenges, and other forms of entertaining content.

8. Business and Entrepreneurship: Entrepreneurs and aspiring business owners are always looking for advice and inspiration. Creators can provide tips on starting and running a business, marketing strategies, and personal productivity.

9. Health and Fitness: People are increasingly interested in living healthy lifestyles, and YouTube is a great resource for fitness tips, workout routines, and healthy eating advice. Creators can share their expertise on various aspects of health and fitness.

10. Travel and Vlogs: Travel vlogs are popular among viewers who want to explore new places and cultures. Creators can document their travels, share tips for planning trips, and provide recommendations for destinations and activities.

Please note that these categories are not mutually exclusive, and creators can often combine elements from multiple niches to create unique and engaging content. The key to success on YouTube is to find a niche that you are passionate about and to create high-quality content that your audience will find valuable.